The Met Office has issued yellow “be aware” warnings for wind and snow in Scotland, Northern Ireland and parts of northwest England from Wednesday.
Some 2cm to 5cm snowfall is expected, increasing to 10cm to 20cm on higher ground.
The wintry showers will continue into Thursday and Friday – when the warnings also cover Wales and eastern England.
Temperatures will drop to between 2-5C (36-41F) in the day and will vary overnight.
They could plummet to -8C and -10C in areas hit by snow, such as northern England and Scotland.
Winds of up to 55mph could affect coastal and hilly areas on Wednesday and Thursday, reaching 75mph across northwest Scotland.
So-called ‘thundersnow’ – where rain associated with a thunderstorm falls as snow – is also possible, said the Met Office.
Lightning could affect power supplies and motorists have also been urged to be prepared for “tricky conditions” and avoid non-essential journeys.
Sky News weather presenter Nazaneen Ghaffar said southern areas of the UK could also get sleet and snow.
“By Thursday frequent wintry showers will push in from the west, with snow expected in western Scotland, northwest England and northwest Wales,” said Ghaffar.
“Wintry showers of sleet and snow may affect eastern and southern parts of the UK as well.
“Friday and Saturday will remain cold, with further outbreaks of rain, sleet and hill snow – mostly across northern and western parts of the UK.
“Southern parts of the UK may experience some light snow flurries too.”
However, Britain’s weather will not be as bad as conditions in mainland Europe, where temperatures as low as -30C have caused dozens of deaths.
SHARE TO WARN YOUR FRIENDS AND FAMILY!